Steering Committee Meeting - 07/2009
From LipidomicsWiki
Monday, 13.07.2009
Time | Monday, 13.07.2009 | |
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08:30 - 08:40 | Introduction / Welcome
(Prof. G. Schmitz, Regensburg) | |
Presentations of the LipidomicNet Scientific Advisory Committee | ||
08:40 - 09:05 | Prof. M. Wenk | Lipidomics, novel tools and applications |
09:05 - 09:35 | Prof. E. Dennis | LIPID MAPS Lipidomics Initiative and Eicosanomics |
09:35 - 09:55 | Prof. D. Brasaemle | The role of perilipin in control of lipolysis |
Work package and deliverable-orientated presentations | ||
| WP 1
(Chair: Prof. G. Schmitz P01) | Scientific management |
09:55-10:05 | J. Jonas (P01) | Scientific Management Report |
10:05-10:30 | Coffee Break | |
| WP 2, together with TF I - IV
(Chair: Prof. C. Thiele) | Enabling technologies |
10:30-10:40 | WP2.1: Dr. G. Liebisch (P01) | Analysis of glycerophosphoplipid species |
10:40-10:50 | WP2.1: M. Scherer (P01) | Analysis of sphingolipid species |
10:50-11:00 | WP 2.3: Dr. J. Hansen/Protagen (P20) | Identification of novel lipidomic targets during weight loss induced tissue remodelling using a planar protein array |
11:00-11:10 | WP 2.4: Prof. C. Thiele (P10) | LD540, a new dye for lipid droplet imaging |
11:10-11:20 | WP 2.4: Dr. J. Weghuber (P24) | Single molecule imaging on lipid droplets |
11:20-11:30 | WP 2.7: Dr. K. Böger (P02) | Early intermediates in lipid droplet biogenesis |
11:30-11:40 | WP 2.4: Dr. M. Grandl (P01) | High content imaging of lipid droplets and phospho-lipidosis in differentiated and lipid loaded human macrophages |
11:40-11:50 | WP 2.4: Z. Torok (P11): | Single molecule imaging of membrane nanostructure and dynamics |
| WP 3, together with TF V
(Chair: Prof. C. Wolfrum P06) | Mouse models of liver and adipose lipid droplet processing |
11:50-12:00 | Prof. Dr. K. van Dijk (P05) | KoWvD_HFDIO.ppt The role of high fat diets in adiposity, insulin sensitivity and hepatic inflammation |
12:00-12:15 | Dr. E. Hajduch (P04). | Caveolin-1 is critical for size enlargment of lipid droplets by regulating the organelle surface composition |
12:15-12:30 | Dr. H. Köfeler (P07) | Lipid analysis of caveolin-null lipid droplets |
12:30-12:40 | Prof. Dr. C. Wolfrum (P06) | Transcriptional control of adipogenesis |
| WP 4, together with TF VI + VII
(Chair: Prof. M. Wakelam P16) | Dysregulation of liver and adipose lipid droplet processing in human diseases |
12:40-12:55 | Prof. Dr. M. Wakelam (P13) | MS analysis of LD content: Standards and preanalytics |
12:55-13:05 | Prof. Dr. Frederik Karpe (P22) | Adipose tissue changes in response to insulin sensitization |
13:05-14:05 | Lunch | |
14:05-14:15 | Dr. P. Ugocsai (P01) | Sphingolipid and glycerophosholipid species and related polymorphic genes are associated with metablic overload risk |
14:15-14:25 | Dr. P. Ugocsai(P01) | Sigruener_final_SC-Meeting_LipidomicNet.ppt ATP10D is a glucosylceramide translocase regulating lipid storage |
14:25-14:40 | PD Dr. M. Fischer | Weight loss dependent modulation of adipose tissue and liver related biomarkers |
14:40-14:50 | Dr. V. Tarabin (P01) | Transcriptional and metabolic changes during adipocyte differentiation |
14:50-15:00 | Prof. A. Dembinska-Kiec (P09) | Changes in metabolism, lipid droplet accumulation and RE stress proteins in transdifferentiating human SVF cells |
15:00-15:10 | Dr. J. McLauchlan (P23) | The impact of modulating lipid metabolism on lipid droplets and the HCV replication cycle |
| WP 5
(Chair: Prof. Schmitz P01) | Lipid droplets and lipid bodies in human macrophages and leukocytes |
15:10-15:20 | WP 5.2: P. Boström MD PhD
(P08 - UGOT) | Lipid Droplets in Human Macrophages Recruit Cytosolic Phospholipase A2 and Promote Secretion of Inflammatory Mediators |
15:20-15:30 | WP 5.1: Dr. J. Ecker (P01) | SteeringC_120709.ppt The role of SREBP-1c mediated induction of lipid metabolism for macrophage differentiation |
15:30-15:40 | WP 5.1: Dr. M. Grandl (P01) | Transcriptomic and Lipidomic analysis of lipid loaded human macrophages with an induction of lipid droplets or lamellar bodies in the endolysosomal compartment |
15:40-15:50 | WP 5.1: Dr. K. Leuthäuser-Jaschinski (P01) / Dr. E. Orsó (P01) | Transcriptomic analysis of lipid-laden human Niemann-Pick disease type C macrophages |
15:50 - 16:00 | WP 5.4: K. Rübsaamen (P01) | Lipidomic analysis of monocytes and granulocytes |
16:00-16:10 | WP 5.4: R. Guttzeit (P01) | Influence of oral fat load on plasma and blood monocytes lipid species and transcriptomics |
16:10-16:35 | Coffee break | |
| WP 6 (Chair: Dr. T. Kolter) | Cellular lipid entry pathways into Lipid Droplets and Lamellar Bodies |
16:35-16:50 | WP 6.3: Dr. T. Kolter (P15) | Analysis of cellular lipid uptake and processing |
16:50-17:00 | WP 6.4: Prof. J. Borlak (P01) | to be completed by WP6 chair |
17:00-17:15 | WP 6.3: Dr. V. Olkkonen (P14) | Lipid binding/transfer proteins with roles in cellular neutral lipid metabolism |
| WP 7, together with TF VIII
(Chair: Dr. L. Martens P16) | Bioinformatics |
17:15-17:35 | Dr. L. Martens (P16) | overview of WP, recapitulation of work in first 6 months, LipidomicNet Wiki / Public availability of SPPs |
17:35-17:45 | Dr. F. Kolpakov (P19, ZORA) | Lipidomics/metabolomics data processing |
17:45-17:55 | Dr. E. Gonzalez Couto
(P21, Integromics) | RT-PCR data processing |
17:55-18:05 | Dr. A. Kowald (P20, PROTAGEN) | PRE_M12DelivReportTalk_001_090713_AKo.ppt Analysing protein chip data |
18:05-18:15 | J. Koopmann (P01) | Microarray data processing |
18:15-18:25 | Dr. A. Kel (P18, BIOBASE) wp3 | P18_BIOBASE_LipidomicNet_Regensburg_July_2009.ppt Mature adipocyte transcriptomics in mouse models of obesity |
| WP 8, together with TF IX
(Chair: Prof. A. Dembinska-Kiec P09) | Dissemination and training |
18:25-18:35 | Dr. I. Wybranska | Progress in realisation of dissemination and training activity in the first year of the project |
19:30 | Meeting of WP-leaders/Management Team and SAC |
Tuesday, 14.07.2009
Time | Tuesday, 14.07.2009 | |
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| Task Forces Reports | |
08:30-08:45 | TF I: Mass-spectrometric and chromatogra-phic methods and preanalytics for molecular lipid species analyses and stable isotope labelling
(Chair: Dr. G. Liebisch / Dr. M. Köfeler) | to be completed by the TF-Chairman/Co-Chairman during the meeting |
08:45-09:00 | TF II: Fluorescence-based lipidomic methods on intact cells, labelling lipidomic antibodies and proteins
(Chair: Prof. C. Thiele) Presentation, discussion and decision | to be completed by the TF-Chairman/Co-Chairman during the meeting |
09:00-09:15 |
TF III: Affinity binder, ELISA and proteomic mass-spectrometric techniques and reagents (Chair: Dr. S. Müllner) | to be completed by the TF-Chairman/Co-Chairman during the meeting |
09:15-09:30 | TF IV: ForceIV_Arrays_TLDA.ppt Gene-, Taqman- and Bead-array reagents and preanalytics (RNA/DNA, Agilent, Affymetrix, Illumina, ABI TLDAs
(Chair: Prof. G. Schmitz) | to be completed by the TF-Chairman/Co-Chairman during the meeting |
09:30-09:45 | TF V: Mouse models
(Chair: Prof. C. Wolfrum) | Animal models of aberrant lipid droplet formation - update
|
09:45-10:00 | TF VI: Clinical trials and human ethics
(Chair: Dr. D. Gasperikova / Dr. J. Ukropec)) | to be completed by the TF-Chairman/Co-Chairman during the meeting |
10:00-10:15 | TF VII: Human/Mouse translational research
(Chair: Prof. G. Schmitz) | to be completed by the TF-Chairman/Co-Chairman during the meeting |
10:15-10:30 | TF VIII: Bioinformatics
(Chair: Dr. L. Martens) | Bioinformatics - overcoming the challenges to bring it all together |
10:30-10:45 | TF IX: Dissemination, training and communication
(Chair Prof. A. Dembinska Kiec. L.) | to be completed by the TF-Chairman/Co-Chairman during the meeting |
10:45-11:15 | Coffee Break | |
11:15-12:00 | Advisory-report of the Scientific Advisory Committee
| |
12:00-13:00 | Varia | |
13:00 | End of meeting |