Glycerophospholipids (GP)

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LIPID MAPS Subclasses


Glycerophospholipids are beside the [[Sphingolipids (SP)] the principal structural components of cellular membranes, with phosphatidylcholine (PC) and sphingomyelin (SPM) being the most abundant. Quantitatively minor membrane phospholipids include the aminoglycerophospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE) and the inositol-glycerophospholipid phosphatidylinositol (PI). Intracellular metabolism and traffic of these lipids are tightly associated with that of cholesterol traffic. The above mentioned phospholipids serve as essential regulators of multiple cellular processes, either directly or by their enzymatic degradation resulting in the formation of bioactive lipid signaling molecules.


Natural sources


Biophysical properties

Biochemical pathways

Biochemical synthesis

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Biological processes associated

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Analysis methods

Chemical synthesis

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