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LipidomicNet-ENOR workshop program

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Day 1 - November 19, 2010


(time frame includes discussion)


08:30 - 08:40 Opening of workshop


Session 1: Oxysterol analysis, sample preparation, data analysis. 

08:40 - 09:10 W. J. Griffith "Analysis of Oxysterols and Bile Acids by Charge-Tagging and LC-MS/MS"
09:10 - 09:40 U. Diczfalusy “The oxysterol 4b-hydroxycholesterol is an endogenous biomarker for CYP3A activity”
09:40 - 10:10 D. Lütjohann “Use of authentic and stable isotope labelled oxysterols and oxyphytosterols in preclinical and clinical studies”

10:10 - 10:40 Coffee break


Session 2: Oxysterols and cellular effects I.
10:40 - 11:10 M. Poirot “Cholesterol-5,6-epoxydes and derivatives in normal and pathological situations”
11:10 - 11:40 J. Vaya “Oxysterols level and type as a mirror to the type of biochemical pathways taken place in the system under investigation: summary from in vitro and in vivo studies”
11:40 - 12:10 V. Olkkonen “Cytoplasmic oxysterol-binding proteins: Sterol transporters or mediators of oxysterol signals?”
12:10 - 12:25 O. Weingaertner “Vascular effects of diet supplementation with plant sterol esters in mice and men”
12:25 - 12:40 J-M. Lobaccaro “Oxysterols and prostate cancer: the concept of yin-yang”

12.40 - 13.40 Lunch

Session 3: Oxysterols and cellular effects II.
13:40 - 14:10 L. Iuliano “Oxysterols as oxidative stress markers”
14:10 - 14:40 G. Lizard “Oxysterols and cell death"
14:40 - 15:10 M. Grandl “Oxidized LDL (Ox-LDL) induces phospholipidosis while enzymatically modified LDL (E-LDL) induces lipid droplets in human macrophages”
15:10 - 15:25 J. Mackrill “Mechanisms by which oxysterols elicit intracellular calcium signals”
15:25 - 15:40 L. Bretillon “The role of 24-hydroxycholesterol and CYP46A1 in the retina”

15.40 - 16.10 Coffee break / poster session


Session 4: The role of oxysterols in diseases.
16.10 - 16.40 H. Guillou “Oxysterol signaling in fatty acid metabolism”
16.40 – 17.10 V. Leoni “Oxysterols as markers of neurodegenerative disease”
17.10 - 17.40 N. O’ Brian “Overview of cholesterol and phytosterol oxides research in University College Cork”
17.40 - 18.10 S. Matysik “Oxysterols in rare human genetic diseases CTX and NPC-1”

19.00 - 20.00 Dinner

20.00 – 22.00 Discussion on nomenclature mass spec lipid species with wine and beer.

Day 2 - November 20, 2010



Session 5: Analysis of oxidized fatty acids and acylglycerols.
09:00 - 09.30 A. Nicolaou “Lipidomics of bioactive oxygenated fatty acid metabolites“
09.30 - 10.00 M. Lagarde “Functional lipidomics of oxidized products from polyunsaturated fatty acids”
10.00 - 10.30 A. Shevchenko “Molecular composition of triacylglycerols by shotgun lipidomics”

10:30 - 11:00 Coffee break


Session 6: Analysis of glycerophospholipid and sphingolipids species as precursor of bioactive lipids.
11.00 - 11.30 A. N. Hunt ”Lipid sensing by Scap and Insig: regulation of lipogenesis in lung alveolar type II epithelial (ATII) cells”
11.30 - 12.00 M. Wakelam “Novel methodology for phosphoinositide analysis"
12.00 - 12.30 G. Liebisch “Analysis of the sphingolipid rheostat”

12:30 - 13:30 Lunch


Session 7: Analysis and function of bioactive glycerophospho-/sphingolipids.
13.30 - 14.00 M. Scherer “Lysophospholipid, Cardiolipin and BMP analysis”
14.00 - 14.30 G. Stuebiger “Analysis of Oxidized Phospholipids by MALDI Mass Spectrometry”
14.30 - 15.00 H. Koefeler “Application of ion cyclotron resonance mass spectrometry on lipidomic analysis of lipid droplets“

15:00 - 15:30 Coffee break / poster session


Session 8: Regulatory lipid species and disease.

15.30 - 16.00 G. Schmitz “Plasmalogens - the neglected regulatory and scavenging lipid species”
16.00 - 16.30 T. Kolter “Sphingolipids and diseases”
16.30 - 17.00 G. Lo Sasso “The role of hepatic oxysterol synthesis and LXR activation in the regulation of proliferating hepatotoxic capacity during liver regeneration”
17.00 - 18.00 General discussion

18.00 - 18.05 Closing of meeting.


Click here to go back to the general information secion of the LipidomicNet-ENOR joint workshop.


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